The year 1973 not only saw the church of Victoria play host to the Eucharistic Congress, but was also the year of the opening of the new seminary in Bayview Avenue, Clayton. This new seminary was constructed in line with the Second Vatican Council directives, where the students would live in smaller groups and have the opportunity to study at the secular universities. This would enable them to obtain degrees in other fields. The Clayton location was chosen because of its proximity to Monash University.
The new college was designed in such a way that the students would live in units or blocks of twenty-five students and one or two staff members. On the new site there were six blocks known as A, B, C, D, E and F. The centerpiece of the Clayton seminary was the chapel where Mass, the liturgy of the hours, and other liturgical prayer focused the whole life of the seminarians. The extensive library, from both Werribee and Glen Waverley, enriched the academic life at Clayton, whilst common rooms and the expansive dining room served the social life of the community and provided opportunities for the seminary to offer hospitality to the wider Catholic community.
The Sisters of St Joseph of Cluny, lived in their own convent and well loved garden. Squash, tennis and basketball courts provided ample opportunity for physical exercise. The Catholic Theological College was situated with the seminary and contained within its new building. There was also a lecture theatre, tutorial rooms, common rooms for staff and students, as well as offices. Catholic Theological College became the academic 'hub' for Corpus Christi College, along with the Oblates of Mary Immaculate (who provided the first Master - Rev. Dr. Austin Cooper), the Salesians of Don Bosco, and the Missionary Society of St. Paul. Later, the Conventual Francisan Friars were received into the theological college community.
The number of students for the new site would be about 135, with the new twenty-five first year students added on to this. The College had been given permission to use the grounds behind the college as a sports oval, which was ideal, because the college had its own football team. They also entered teams in the local basketball and squash competitions.
Some of the Werribee students moved in, in early March and they helped set up the rooms and living areas before the remaining students arrived.
The day of the opening saw a number of dignitaries from all over Australia and some from overseas. Cardinal Wright from United States of America, opened the seminary as part of the Eucharistic Congress. Cardinal Knox addressed the assembled people and spoke about the new seminary and also the Congress.
Corpus Christi College Clayton counts among its alumni: Archbishop of Brisbane, Mark Coleridge and Archbishop of Canberra-Goulburn Christopher Prowse. Other alumni include the late Bishop of Sandhurst, Joseph Grech and Auxiliary Bishop of Melbourne Peter Elliott.
Archbishop of Perth, Timothy Costelloe SDB, also attended Catholic Theological College at the Clayton campus.